Hypertension, commonly referred to as high blood pressure, is a major public health concern and a leading contributor to cardiovascular diseases, stroke, and kidney failure. Traditional approaches to hypertension management include dietary modifications, physical activity, and medications. However, emerging research suggests that the gut microbiome—the diverse community of microorganisms residing in the human digestive tract—may play a pivotal role in blood pressure regulation. This article explores the science behind microbiome-based therapies, including the potential of probiotics and other microbiome-targeted interventions, to determine whether these approaches represent a credible new frontier or mere speculation.
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Hypertension, commonly referred to as high blood pressure, is a leading global health concern, affecting more than 1.28 billion adults worldwide, according to the World Health Organization (WHO). While its causes have traditionally been attributed to genetic predisposition, diet, lifestyle, and environmental factors, emerging research highlights the role of gut microbiota as a significant contributor to blood pressure regulation. Gut microbiota—the trillions of microorganisms residing in the gastrointestinal tract—play an intricate role in maintaining overall health, influencing metabolic, immune, and cardiovascular functions. This article delves into the emerging evidence linking gut health and hypertension, explores the underlying mechanisms, and discusses future therapeutic possibilities targeting the gut microbiota.