Hypertension, or high blood pressure, is one of the leading causes of cardiovascular disease worldwide, affecting over 1.28 billion adults, according to the World Health Organization (WHO). While factors like diet, physical activity, and stress are well-established contributors to hypertension, an emerging area of interest is the role of gut health. The gut microbiome—an ecosystem of trillions of microorganisms—plays a vital role in regulating various aspects of health, including blood pressure. Probiotics, live beneficial bacteria found in certain foods and supplements, are increasingly recognized for their potential to manage hypertension.
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Hypertension, often called the “silent killer,” is a global health challenge affecting more than 1.28 billion adults worldwide, as reported by the World Health Organization (WHO). Despite advancements in pharmacological treatments and lifestyle interventions, many patients struggle to achieve optimal blood pressure control. Increasing attention has turned to the endothelium, a thin layer of cells lining blood vessels, as a key player in hypertension pathophysiology. Dysfunction of the endothelium is recognized as an early and critical factor in the development and progression of high blood pressure. This article explores how targeting endothelial dysfunction could revolutionize hypertension management, delving into the mechanisms, therapeutic strategies, and emerging treatments aimed at restoring vascular health.