Hypertension, or high blood pressure, is one of the most prevalent chronic conditions globally, affecting more than 1.28 billion adults according to the World Health Organization (WHO). While the genetic component of hypertension has long been recognized, recent advancements in the field of epigenetics have highlighted how environmental and lifestyle factors can influence gene expression and, in turn, affect blood pressure regulation. Understanding the interplay between genes and the environment offers exciting opportunities for personalized hypertension management. This article explores the science of epigenetics, how it relates to hypertension, and the potential for lifestyle interventions and emerging therapies to positively influence blood pressure.