Hypertension, or high blood pressure, is a global health crisis affecting over 1.28 billion adults, according to the World Health Organization (WHO). Despite the availability of effective medications and lifestyle interventions, managing hypertension remains a challenge for many patients due to issues such as medication adherence, side effects, and limited efficacy in resistant cases. Emerging technologies, particularly nanotechnology, are revolutionizing the field of medicine by offering innovative solutions for diagnosis, drug delivery, and disease monitoring. In hypertension management, nanotechnology—through its application in nanomedicine—holds the promise of improving treatment outcomes by enhancing drug efficacy, reducing side effects, and enabling personalized care. This article explores how nanotechnology is advancing hypertension management and its potential to transform cardiovascular health.